A widespread problem is the game deleting all installed mods upon launch. After you place your mods in the folder and start the game, they can vanish during the loading process. One workaround involves modifying folder permissions:

__full__ — The Binding Of Isaac Repentance Cracked Mods

A widespread problem is the game deleting all installed mods upon launch. After you place your mods in the folder and start the game, they can vanish during the loading process. One workaround involves modifying folder permissions: