No. Resident Evil 5 was never released for the PlayStation Portable (PSP). Because the PPSSPP emulator only plays native PSP games, there is no official Resident Evil 5 ISO or ZIP file that will run on this emulator. Beware of Fake Download Links

3. The Native Unofficial Android Port (NVIDIA Shield Source)

Requires a paid subscription and a continuous, fast internet connection. Summary: Stay Safe, Play Smart

Because the PPSSPP software only emulates original PSP hardware, you cannot run the official PlayStation 3, Xbox 360, or PC version of Resident Evil 5 directly inside the emulator.

These provide the survival horror experience you’re seeking without searching for non-existent PSP versions.