Wilms Tumor | Ppt New !full!
: Hematogenous metastases present (lungs, liver, bone, or brain). Stage V : Bilateral renal involvement at diagnosis. Treatment Strategies
: Used to distinguish histological subtypes and predict how the tumor will respond to chemotherapy before surgery. wilms tumor ppt new
| Type | Definition | Prognostic Implication | |------|------------|----------------------| | | Anaplasia involving circumscribed regions confined to the kidney | Outcomes are favorable with appropriate therapy | | Diffuse Anaplastic Wilms Tumor (DAWT) | Anaplastic changes not circumscribed or present in any extrarenal site | Poor outcomes, especially in stage III and IV tumors | : Hematogenous metastases present (lungs, liver, bone, or
Indicated for bilateral disease (Stage V) or patients with syndromic predispositions to protect long-term renal function. Chemotherapy : Hematogenous metastases present (lungs